Homogenizers and Immersion Blenders
Devices designed for overhead immersion into substances; ideal for pulverization of plant/animal tissue, grain/seed, sample prep, and more. Includes accessories such as generator probes of varying tips, stand assemblies, bead mill tubes, and more.
Homogenizers can be used with tissue, plant, food, soil, and other sample types. Homogenization is a common sample preparation step for analyzing nucleic acids, proteins, cells, metabolism, pathogens, and other targets.
Cell fractionation releases the contents of cells, and newer methods have been designed to consider quality and environmental aspects, cross-contamination, aerosol generations, infection risk, and noise levels. Different methods have been developed for disrupting cell walls and other structures. These include bead mills, sonication, rotor-stator mechanical, high pressure, and other physical methods.
For biological work, sonication may adequately disrupt or deactivate biological material via the process of sonoporation. Sonic dismembrators can break up cells and fragment DNA molecules by subjecting the sample to ultrasonic waves that create small fragments.
Some substances can be mechanically homogenized using beads and other small pieces of metal or minerals. The sample is added to a vial that contains these small particles; the tubes are then rapidly agitated, which breaks down the materials. Depending on the equipment, many samples can be processed simultaneously with this method.
Another mechanical homogenization method is the rotor-stator; these devices have a fast-spinning inner rotor and a stationary outer sheath (stator). Samples are subjected to tearing, shear fluid forces, and cavitation (bubble formation and collapse). A rotor-stator processes a single sample at a time; high-throughput and continuous use models are available.
An immersion blender has an electric motor that powers rotating blades at the end of a shaft. The device is lowered into the sample or mixture and the motor activated. The device may be hand-held or clamped to a stand.
Homogenizer packages are also available for motorized methods.
Med Vet International Amber Plastic Graduated Ovals 8 Oz., 25/Pack
Amber Plastic Graduated Ovals with twist off child resistant caps. Lightweight transparent amber ovals graduated in ounces and milliliters
Bellco Glass, Inc. The conical tissue homogenizer is designed for use with homogenizing motors. Ideal for tissues such as muscle, heart and lung. The conical tissue homogenizer has a large area for most efficient grinding. The clearance between pestles is .004-.006". Ca
The conical tissue homogenizer is designed for use with homogenizing motors. Ideal for tissues such as muscle, heart and lung. The conical tissue homogenizer has a large area for most efficient grinding. The clearance between pestles is .004-.006". Ca
Covaris Inc tissueTUBE TT2 & Plug Case (300)
tissueTUBEs for sample collection, storage, pulverization, and transfer. For samples of mass 2 g. For use with the CP02 cryoPREP® Automated Dry Pulverizer and Holder tissueTUBE TT1 & tissueTUBE Extra Thick.
Uline Front Squeegee Blade For Compact Auto Floor Scrubber - 20"
Front Squeegee Blade For Compact Auto Floor Scrubber-20IN
Next Advance Inc NAVY LYSIS KIT 250. BEAD LYSIS
Navy Lysis Kit 250. Bead lysis kits for the homogenization of large, tough samples. Pack of 250, 1.5mL Eppendorf Safe-Lock tubes prefilled with stainless steel beads.
Electron Microscopy Sciences Upper Drive Wheel for Model 865 Diamond Band Saw
For use with Model 865 Daimond Band Saw (50182-65).
Ops Diagnostics BAWG 4000-200-18 ACID WASH 4MM SILICA BEADS
These large silica beads are useful for homogenizing soft tissues in harsh buffers. Beads are acid washed to remove impurities and silica dust. Silica beads are a cost effective alternative to zirconium oxide and stainless steel when high density media is unnecessary or impractical. Packaged in bottles of 200 grams.
Alkali Scientific D1000 Handheld Homogenizer
Alkalis Hand-held Homogenizer with 5mm and 7mm Generator Heads the D1000 is designed to rapidly homogenize emulsify suspend and disrupt biological samples Ideal for use with microtubes the homogenizer works well with samples from 0 1ml to 250ml (depending upon the generator probe used) The D1000 is a rotor stator homogenizer and works by drawing the sample in liquid into the generator probe with the variable speed rotor and then forcing it out through the slots in the stator This achieves mechanical shearing of the sample As the sample is repeatedly drawn up and forced through the stator additional shearing takes place Most samples are completely homogenized in 30 seconds or less A powerful 130W motor drives the rotor at speeds from 8500 to 30000 rpm Speed is adjustable in sixsteps to meet sample processing needs A separate on/off switch allows the homogenizer to be left at the appropriate setting Generator probes are available in four sizes The 5mm and 7mm diameter probes h
Medchemexpress LLC LM10 | 1316695-35-8 | 99.9% | 229.22 | 100 MG
LM10 is a potent inhibitor of tryptophan 2,3-dioxygenase (TDO). Tryptophan 2,3-dioxygenase (TDO) is an unrelated hepatic enzyme that also degrades tryptophan along the kynurenine pathway. LM10 has the potential for the research of cancer diseases.
- Prevents the growth of TDO-expressing P815 tumor cells and promotes better rejection of control clone P815B cl1, which does not express TDO.
- Displays a good TDO inhibition (Ki = 5.6 μM) with a competitive inhibition profile.
- Does not inhibit IDO and has a high solubility and bioavailability without obvious signs of toxicity.
- The plasma concentration after oral administration is about 40 times above the IC50 measured in the cellular assay performed with the physiological concentration of plasma tryptophan.